本課程主要介紹在細胞生物學和實驗設計的關鍵概念,並結合醫學 相關的例子,以幫助闡明細胞生物學、健康、與人類老化、疾病之 間的聯繫。課程內容包括細胞生物學基本概念,生物膜結構,離子 和小分子的跨膜運輸,蛋白運輸進入細胞膜和胞器,囊泡運輸,分 泌和內吞作用,信號轉導和G蛋白偶聯受體,控制基因表達之訊號傳 遞,細胞系統和運動,真核細胞週期,細胞死亡,免疫學和癌症學 等章節。
This course introduces the key concepts in cell biology and their experimen tal underpinnings, and incorporate medically relevant examples where appr opriate to help illustrate the connections between cell biology and health an d human disease. The course covers basic concept of cell biology, culturing , visualizing, and perturbing cells, biomembrane structure, transmembrane t ransport of ions and small molecules, moving proteins into membranes and organelles, vesicular traffic, secretion, and endocytosis, signal transduction and G protein-coupled receptors, signaling pathways that control gene exp ression, cell organization and movement, the eukaryotic cell cycle, and cell death, immunology, and cancer.